Evolution of contrast agents for ultrasound imaging and ultrasound-mediated drug delivery

  title={Evolution of contrast agents for ultrasound imaging and ultrasound-mediated drug delivery},
  author={Vera Paefgen and Dennis Doleschel and Fabian Kiessling},
  booktitle={Front. Pharmacol.},
Ultrasound (US) is one of the most frequently used diagnostic methods. It is a non-invasive, comparably inexpensive imaging method with a broad spectrum of applications, which can be increased even more by using bubbles as contrast agents (CAs). There are various different types of bubbles: filled with different gases, composed of soft- or hard-shell materials, and ranging in size from nano- to micrometers. These intravascular CAs enable functional analyses, e.g., to acquire organ perfusion in… CONTINUE READING
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