Evolution of cis-regulatory elements in duplicated genes of yeast.

@article{Papp2003EvolutionOC,
  title={Evolution of cis-regulatory elements in duplicated genes of yeast.},
  author={Bal{\'a}zs Papp and Csaba P{\'a}l and Laurence D Hurst},
  journal={Trends in genetics : TIG},
  year={2003},
  volume={19 8},
  pages={
          417-22
        }
}
An increasing number of studies report that functional divergence in duplicated genes is accompanied by gene expression changes, although the evolutionary mechanism behind this process remains unclear. Our genomic analysis on the yeast Saccharomyces cerevisiae shows that the number of shared regulatory motifs in the duplicates decreases with evolutionary time, whereas the total number of regulatory motifs remains unchanged. Moreover, genes with numerous paralogs in the yeast genome do not have… CONTINUE READING

Figures, Tables, and Topics from this paper.

Explore Further: Topics Discussed in This Paper

Citations

Publications citing this paper.
SHOWING 1-10 OF 74 CITATIONS, ESTIMATED 69% COVERAGE

Functional Redundancy and Expression Divergence among Gene Duplicates in Yeast

VIEW 9 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Uncovering genetic regulatory network divergence between duplicate genes using yeast eQTL landscape.

  • Journal of experimental zoology. Part B, Molecular and developmental evolution
  • 2009
VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

The limits of subfunctionalization

  • BMC Evolutionary Biology
  • 2007
VIEW 5 EXCERPTS
CITES RESULTS & BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2003
2018

CITATION STATISTICS

  • 8 Highly Influenced Citations