Evolution of blood-brain-barrier permeability after acute ischemic stroke

@inproceedings{Merali2017EvolutionOB,
  title={Evolution of blood-brain-barrier permeability after acute ischemic stroke},
  author={Zamir Merali and Kun Huang and David Mikulis and Frank Silver and Andrea Kassner},
  booktitle={PloS one},
  year={2017}
}
The dynamics of BBB permeability after AIS in humans are not well understood. In the present study we measured the evolution of BBB permeability after AIS in humans using MRI. Patients presenting to our institution with a diagnosis of AIS underwent a single dynamic contrast-enhanced MRI (DCE-MRI) sequence to measure BBB permeability during their initial workup. Forty-two patients were included in the final analysis. The patient sample underwent DCE-MRI at a mean time of 23.8hrs after the onset… CONTINUE READING

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