Evolution of biocatalysis 1. Possible pre-genetic-code RNA catalysts which are their own replicase

@article{Visser2004EvolutionOB,
  title={Evolution of biocatalysis 1. Possible pre-genetic-code RNA catalysts which are their own replicase},
  author={Cornelis M. Visser},
  journal={Origins of life},
  year={2004},
  volume={14},
  pages={291-300}
}
  • C. Visser
  • Published 2004
  • Chemistry, Medicine
  • Origins of life
A search for a possible chemical mechanism for pre-genetic-code phosphorylation, phosphoric anhydride formation and subsequent evolution of catalysts based upon oligoribonucleotides has resulted in a plausible scheme for pre-genetic-code evolution of self-replicating catalysts, independent of coded polypeptides. Only known chemistry of extant cofactors (coenzymes and prosthetic groups) and models thereof has been used for construction of this theoretical scheme. 
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