Evolution of aneuploidy up to Day 4 of human preimplantation development.

@article{Mertzanidou2013EvolutionOA,
  title={Evolution of aneuploidy up to Day 4 of human preimplantation development.},
  author={Afroditi Mertzanidou and Claudia Spits and Ha Thi Nguyen and Hilde van de Velde and Karen Dora Sermon},
  journal={Human reproduction},
  year={2013},
  volume={28 6},
  pages={1716-24}
}
STUDY QUESTION What is the incidence of aneuploidy and mosaicism in all cells of top-quality Day-4 embryos analysed by array-based comparative genomic hybridization (array CGH)? SUMMARY ANSWER Our data show extensive abnormalities in Day-4 embryos. WHAT IS KNOWN ALREADY Numerous studies on human embryos at Day 3 and Day 5 of development show that they… CONTINUE READING