Evolution of anaphylatoxins, their diversity and novel roles in innate immunity: insights from the study of fish complement.

@article{Sunyer2005EvolutionOA,
  title={Evolution of anaphylatoxins, their diversity and novel roles in innate immunity: insights from the study of fish complement.},
  author={Jorge Sunyer and Hani Boshra and Jinrui Li},
  journal={Veterinary immunology and immunopathology},
  year={2005},
  volume={108 1-2},
  pages={77-89}
}
Anaphylatoxins are small molecules ( approximately 9 kDa) that are generated as a result of the activation of the complement system. These molecules play an important role in inflammation, and they are responsible for the activation of various innate and adaptive immune processes. The study of these important inflammatory molecules has been restricted to mammalian species so far. Recent studies have shown that teleost fish, unlike any other known animal species, contain multiple forms of the… CONTINUE READING
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