Evolution of adverse changes in stored RBCs

@article{BennettGuerrero2007EvolutionOA,
  title={Evolution of adverse changes in stored RBCs},
  author={E. Bennett-Guerrero and T. Veldman and A. Doctor and M. Telen and T. Ortel and T. Reid and M. A. Mulherin and Hongmei Zhu and R. D. Buck and R. Califf and T. McMahon},
  journal={Proceedings of the National Academy of Sciences},
  year={2007},
  volume={104},
  pages={17063 - 17068}
}
Recent studies have underscored questions about the balance of risk and benefit of RBC transfusion. A better understanding of the nature and timing of molecular and functional changes in stored RBCs may provide strategies to improve the balance of benefit and risk of RBC transfusion. We analyzed changes occurring during RBC storage focusing on RBC deformability, RBC-dependent vasoregulatory function, and S-nitrosohemoglobin (SNO-Hb), through which hemoglobin (Hb) O2 desaturation is coupled to… Expand

Paper Mentions

Blog Post
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ConditionsBlood Transfusion, Endothelial Physiopathology, Nitric Oxide, (+1 more)
InterventionDrug, Procedure
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Red blood cell storage lesion.
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