Evolution of a protein superfamily: Relationships between vertebrate lens crystallins and microorganism dormancy proteins

@article{Wistow2005EvolutionOA,
  title={Evolution of a protein superfamily: Relationships between vertebrate lens crystallins and microorganism dormancy proteins},
  author={G. Wistow},
  journal={Journal of Molecular Evolution},
  year={2005},
  volume={30},
  pages={140-145}
}
  • G. Wistow
  • Published 2005
  • Biology, Medicine
  • Journal of Molecular Evolution
SummaryA search of sequence databases shows that spherulin 3a, an encystment-specific protein ofPhysarum polycephalum, is probably structurally related to the β- and γ-crystallins, vertebrate ocular lens proteins, and to Protein S, a sporulation-specific protein ofMyxococcus xanthus. The β- and γ-crystallins have two similar domains thought to have arisen by two successive gene duplication and fusion events. Molecular modeling confirms that spherulin 3a has all the characteristics required to… Expand
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Four small Drosophila heat shock proteins are related to each other and to mammalian alpha-crystallin.
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  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1982
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