Evolution of Xmrk: an oncogene, but also a speciation gene?

@article{Schartl2008EvolutionOX,
  title={Evolution of Xmrk: an oncogene, but also a speciation gene?},
  author={Manfred Schartl},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  year={2008},
  volume={30 9},
  pages={822-32}
}
Genes that exert their function when they are introduced into a foreign genetic background pose many questions to our current understanding of the forces and mechanisms that promote either the maintenance or divergence of gene functions over evolutionary time. The melanoma inducing Xmrk oncogene of the Southern platyfish (Xiphophorus maculatus) is a stable constituent of the genome of this species. It displays its tumorigenic function, however, almost exclusively only after inter-populational… CONTINUE READING
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