Evolution of X-Degenerate Y Chromosome Genes in Greater Apes: Conservation of Gene Content in Human and Gorilla, But Not Chimpanzee

  title={Evolution of X-Degenerate Y Chromosome Genes in Greater Apes: Conservation of Gene Content in Human and Gorilla, But Not Chimpanzee},
  author={H. Goto and L. Peng and K. Makova},
  journal={Journal of Molecular Evolution},
  • H. Goto, L. Peng, K. Makova
  • Published 2008
  • Biology, Medicine
  • Journal of Molecular Evolution
  • Compared with the X chromosome, the mammalian Y chromosome is considerably diminished in size and has lost most of its ancestral genes during evolution. Interestingly, for the X-degenerate region on the Y chromosome, human has retained all 16 genes, while chimpanzee has lost 4 of the 16 genes since the divergence of the two species. To uncover the evolutionary forces governing ape Y chromosome degeneration, we determined the complete sequences of the coding exons and splice sites for 16 gorilla… CONTINUE READING
    28 Citations
    The Y chromosomes of the great apes
    • 10
    • PDF
    Multicopy gene family evolution on primate Y chromosomes
    • 18
    • PDF
    Origins and functional evolution of Y chromosomes across mammals
    • 336
    • PDF
    Sex Chromosomes Evolution in Mammals
    • 1
    The sex-specific region of sex chromosomes in animals and plants
    • 19
    • Highly Influenced
    • PDF
    Expression Evolution of Ancestral XY Gametologs across All Major Groups of Placental Mammals
    • PDF
    Male-specific region of the bovine Y chromosome is gene rich with a high transcriptomic activity in testis development
    • 57
    • PDF


    Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee
    • 174
    • Highly Influential
    • PDF
    The evolutionary history of human and chimpanzee Y-chromosome gene loss.
    • 28
    • Highly Influential
    • PDF
    Divergence of the genes on human chromosome 21 between human and other hominoids and variation of substitution rates among transcription units
    • Jinxiu Shi, Huifeng Xi, +17 authors W. Huang
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 2003
    • 43
    • Highly Influential
    • PDF
    Novel Gene Acquisition on Carnivore Y Chromosomes
    • 76
    • PDF
    More genes underwent positive selection in chimpanzee evolution than in human evolution
    • 212
    • Highly Influential
    • PDF
    Abundant gene conversion between arms of palindromes in human and ape Y chromosomes
    • 549
    • PDF
    Genomic divergences between humans and other hominoids and the effective population size of the common ancestor of humans and chimpanzees.
    • 694
    • PDF
    High levels of Y-chromosome nucleotide diversity in the genus Pan
    • 152
    • PDF
    The DNA sequence of the human X chromosome
    • 1,001
    • PDF