Evolution of Parkinson's disease during 4 years of bilateral deep brain stimulation of the subthalamic nucleus.

@article{stergaard2006EvolutionOP,
  title={Evolution of Parkinson's disease during 4 years of bilateral deep brain stimulation of the subthalamic nucleus.},
  author={Karen \Ostergaard and Niels Aa Sunde},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={2006},
  volume={21 5},
  pages={624-31}
}
Patients with advanced Parkinson's disease (PD) and motor complications can obtain significant symptom improvement by deep brain stimulation (DBS) of the subthalamic nucleus (STN). Very little is published, however, about long-term effect and disease evolution during DBS. We performed a 4-year prospective study of the first 22 consecutive patients treated with STN DBS. The patients were evaluated with Unified Parkinson's Disease Rating Scale Part II to VI and a patient diary concerning on-off… CONTINUE READING