Evolution of Neuromodulation

@article{Gildenberg2005EvolutionON,
  title={Evolution of Neuromodulation},
  author={Philip L. Gildenberg},
  journal={Stereotactic and Functional Neurosurgery},
  year={2005},
  volume={83},
  pages={71 - 79}
}
  • P. Gildenberg
  • Published 1 August 2005
  • Psychology, Medicine
  • Stereotactic and Functional Neurosurgery
Neuromodulation, as defined as the use of electrical stimulation by implanted stimulators to treat various neurological conditions, has developed gradually from long experience with electrical stimulation of the nervous system. Indications are still evolving, and the field is advancing at an ever increasing rate. 
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104 Citations
Highly Influential Citations
4
Background Citations
25
Methods Citations
5
Results Citations
2

104 Citations

Citation Type

Citation Type

Advanced neuroimaging techniques for central neuromodulation.
Deep brain stimulation an effective treatment of many neurologic conditions such as Parkinson disease, essential tremor, dystonia, and obsessive-compulsive disorder. Structural and functional… Expand
Electricity in the treatment of nervous system disease.
TLDR
Electrotherapy has reached a degree of sophistication where it can be applied relatively safely and effectively in a variety of nervous system diseases, including pain, movement disorders, epilepsy, Tourette syndrome, psychiatric disease, addiction, coma, urinary incontinence, impotence, infertility, respiratory paralysis, tinnitus and blindness. Expand
Deep Brain Stimulation
TLDR
The clinical efficacy of DBS has preceded scientific understanding of its therapeutic mechanisms of action and a number of conflicting hypotheses are currently under investigation. Expand
Neuromodulation Technologies and the Regulation of Forms of Life: Exploring, Treating, Enhancing
TLDR
DBS implementation in a French neuroscience ward is described and the different forms of practice that structure and promote the development and circulation of this neuromodulation technology are described. Expand
The Impact of Subthalamic Deep Brain Stimulation on Nigral Neuroprotection—Myth or Reality?
  • D. Harnack, A. Kupsch
  • Medicine
  • Neuromodulation : journal of the International Neuromodulation Society
  • 2010
TLDR
If modulation of the subthalamic nucleus (STN) could be a target for neuroprotection in Parkinson's disease (PD) is summarized. Expand
Origin and Evolution of Deep Brain Stimulation
TLDR
The potentials of the DBS for therapeutic use are fascinating, but there are still many unresolved technical and ethical problems, concerning the identification of the targets for each disease, the selection of the patients and the evaluation of the results. Expand
Neuromodulation - Science and Practice in Epilepsy: Vagus Nerve Stimulation, Thalamic Deep Brain Stimulation, and Responsive NeuroStimulation
TLDR
The authors review some of the science behind the most frequently used medical devices for neuromodulation, the evidence that lead to their adoption, a delineation of the populations that often benefit from these devices, and perspectives on clinical practice to optimize benefit in treatment of seizures. Expand
Deep brain stimulation, vagal nerve stimulation and transcranial stimulation: An overview of stimulation parameters and neurotransmitter release
TLDR
This review aims to compile stimulation techniques that are currently in use to explore or treat neurological disorders by combining stimulation parameters developed in animal models and stimulation techniques used in human treatment, resulting in a greater understanding of the mechanisms and neurobiological effects of neuromodulation devices. Expand
Pathways of Translation: Deep Brain Stimulation
TLDR
How the quest to expand its applications and improve outcomes is taking DBS from the bedside back to the bench is discussed. Expand
The History of Deep Brain Stimulation
TLDR
DBS had been used since the 1950s for treatment of psychiatric patients, but this practice was abandoned due to ethical objections, as well as the introduction of neuroleptics, and thereafter for the treatment of Parkinson’s disease, dystonias, obsessive–compulsive disorder and epilepsy. Expand
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