Evolution of NMDA receptor cytoplasmic interaction domains: implications for organisation of synaptic signalling complexes

@article{Ryan2007EvolutionON,
  title={Evolution of NMDA receptor cytoplasmic interaction domains: implications for organisation of synaptic signalling complexes},
  author={Tom{\'a}s J Ryan and Richard D Emes and Seth G. N. Grant and N. Hennakao Komiyama},
  journal={BMC Neuroscience},
  year={2007},
  volume={9},
  pages={6 - 6}
}
Glutamate gated postsynaptic receptors in the central nervous system (CNS) are essential for environmentally stimulated behaviours including learning and memory in both invertebrates and vertebrates. Though their genetics, biochemistry, physiology, and role in behaviour have been intensely studied in vitro and in vivo, their molecular evolution and structural aspects remain poorly understood. To understand how these receptors have evolved different physiological requirements we have… CONTINUE READING

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