Evolution of HIV resistance mutations in patients maintained on a stable treatment regimen after virologic failure.


OBJECTIVE We compared the rate of emergence of thymidine analogue mutations (TAMs) and major protease inhibitor mutations in adherent patients who remained on stable treatment with a thymidine analogue and/or protease inhibitor after the onset of virologic failure. DESIGN Follow-up genotypic resistance testing was done using archived plasma obtained from… (More)


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