Evolution of Genomic Structures on Mammalian Sex Chromosomes

  title={Evolution of Genomic Structures on Mammalian Sex Chromosomes},
  author={Yukako Katsura and Mineyo Iwase and Yoko Satta},
  booktitle={Current genomics},
Throughout mammalian evolution, recombination between the two sex chromosomes was suppressed in a stepwise manner. It is thought that the suppression of recombination led to an accumulation of deleterious mutations and frequent genomic rearrangements on the Y chromosome. In this article, we review three evolutionary aspects related to genomic rearrangements and structures, such as inverted repeats (IRs) and palindromes (PDs), on the mammalian sex chromosomes. First, we describe the stepwise… CONTINUE READING