Evolution of Gab family adaptor proteins.

  title={Evolution of Gab family adaptor proteins.},
  author={Tetteh Abbeyquaye and Juan Riesgo-Escovar and Thomas Raabe and Justin R. Thackeray},
The Gab/dos/Soc-1 proteins form a family of multi-adaptor/scaffolding proteins involved in receptor tyrosine kinase signaling. To further understanding of the Gab family and the Drosophila Dos protein in particular, we isolated a dos homolog from both Drosophila pseudoobscura and Drosophila virilis and compared their gene structures and protein sequences with the rest of the Gab family. The presence of two conserved introns confirmed that the dos and gab genes are orthologous, but the… CONTINUE READING


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