Evolution of Evolvability in a Developmental Model

@inproceedings{Draghi2008EvolutionOE,
  title={Evolution of Evolvability in a Developmental Model},
  author={Jeremy A. Draghi and G{\"u}nter P. Wagner},
  booktitle={Evolution; international journal of organic evolution},
  year={2008}
}
  • J. Draghi, G. Wagner
  • Published in
    Evolution; international…
    1 February 2008
  • Biology, Medicine
Abstract Evolvability, the ability of populations to adapt, can evolve through changes in the mechanisms determining genetic variation and in the processes of development. Here we construct and evolve a simple developmental model in which the pleiotropic effects of genes can evolve. We demonstrate that selection in a changing environment favors a specific pattern of variability, and that this favored pattern maximizes evolvability. Our analysis shows that mutant genotypes with higher… Expand

Topics from this paper

The evolutionary dynamics of evolvability in a gene network model
TLDR
The results conclusively demonstrate that fluctuating natural selection can increase the capacity of model gene networks to adapt to new environments and suggest that the evolution of evolvability can have a pervasive influence on many aspects of organisms. Expand
Mechanisms and selection of evolvability: experimental evidence.
TLDR
There is accumulating experimental evidence that some traits can increase the evolvability of a genotype and that these traits do influence evolutionary outcomes, and the potential for traits that influence evolvent to arise and be selected is discussed. Expand
The Relationship Between Evolvability and Robustness in the Evolution of Boolean Networks
TLDR
This paper examines a potential consequence of observations that a large bias in certain areas of genotype space will lead to increased robustness in corresponding phenotypes, as well as investigating the evolution of boolean networks in environments which fluctuate between task targets. Expand
Evolution and evolvability: celebrating Darwin 200
TLDR
Perhaps the most potentially confusing aspects of the concept of evolvability are seen in the relationship between evolVability and robustness. Expand
Evolutionary Capacitance Emerges Spontaneously during Adaptation to Environmental Changes.
TLDR
This work document the evolution of increased evolvability in a fluctuating environment despite using a regime that precludes, by design, the adaptive evolution of evolVability, via a mechanism that is called emergent evolutionary capacitance. Expand
Evolutionary capacitance emerges spontaneously during adaptation to environmental changes
TLDR
It is shown that environmental change can cause the evolution of increased evolvability, despite the use of a strong-selection weak mutation regime that precludes, by design, the adaptive evolution of evolVability. Expand
The inheritance of process: a dynamical systems approach.
  • J. Jaeger, D. Irons, N. Monk
  • Biology, Medicine
  • Journal of experimental zoology. Part B, Molecular and developmental evolution
  • 2012
TLDR
It is argued that an explicit treatment of this genotype-phenotype map in terms of dynamical systems theory can provide an integrated understanding of evolution and development, and a conceptual framework is described, which demonstrates how development determines the probability of possible phenotypic transitions-and hence the evolvability of a biological system. Expand
The Emergence of Canalization and Evolvability in an Open-Ended, Interactive Evolutionary System
TLDR
It is revealed that genomes entrench certain dimensions of variation that were frequently explored during their evolutionary history, and it is shown that these organizational properties correlate with increased fitness. Expand
Viral host-range evolvability changes in response to fluctuating selection
TLDR
It is found a single mutation in the receptor-binding protein was sufficient to render these strains resistant to evolution and did so by counteracting a receptor- binding trade-off associated with generalism, and cost-free generalization allowed for reduced evolution and evolvability while maximizing success in both environments. Expand
Evolution of adaptive phenotypic variation patterns by direct selection for evolvability
TLDR
A population genetic model of how natural selection acts on relationship loci, or relationship Quantitative Trait Loci, shows a mechanism by which natural selection can directly enhance the evolvability of complex organisms along lines of adaptive change. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 72 REFERENCES
Evolvability is a selectable trait.
  • David J. Earl, M. Deem
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2004
TLDR
This work describes how evolvability can be an object of Darwinian selection, emphasizing the collective nature of the process, and quantifies the theory with computer simulations of protein evolution. Expand
Evolution of evolvability via adaptation of mutation rates.
TLDR
The results suggest that mutation rate is a control parameter that governs a transition between two qualitatively different phases of evolution, an ordered phase characterized by punctuated equilibria of diversity, and a disordered phase of characterized by noisy fluctuations around an equilibrium diversity. Expand
The evolution of evolvability in genetic linkage patterns.
TLDR
A simple model of genetic interactions, implemented in an evolutionary simulation, demonstrates that clustering of epistatically interacting genes increases the rate of adaptation, and can reorganize linkage patterns from random gene ordering into this more modular organization, thereby facilitating adaptation. Expand
Pleiotropic mutation, modularity and evolvability
  • C. Griswold
  • Biology, Medicine
  • Evolution & development
  • 2006
TLDR
Results are presented that suggest the rate of evolution of a phenotypic character may not decline when that character is pleiotropically associated to an increasing number of other characters, provided that the characters are under pure directional selection such that they are far from their optima relative to the average magnitude of a mutation. Expand
THE MUTATION MATRIX AND THE EVOLUTION OF EVOLVABILITY
TLDR
This work uses analytical theory and simulation-based models to examine the evolution of the mutational correlation, rμ, the key parameter determining the nature of genetic constraints imposed by M, and results indicate that evolvability can evolve in natural systems in a way that tends to result in alignment of the G-matrix, the M- matrix, and the adaptive landscape, and that such evolution tends to stabilize the G -matrix over evolutionary time. Expand
PERSPECTIVE: COMPLEX ADAPTATIONS AND THE EVOLUTION OF EVOLVABILITY
TLDR
It is proposed that the genotype‐phenotype map can evolve by two main routes: epistatic mutations, or the creation of new genes, a common result for organismic design is modularity. Expand
Evolution of Genetic Potential
TLDR
Using a transparent mathematical model, the concept of genetic potential is illustrated and it is shown that as environmental variability decreases, the evolving population reaches three distinct steady state conditions: organismal flexibility, genetic potential, and genetic robustness. Expand
The Evolution of Mutation Rate in Finite Asexual Populations
TLDR
This model describes the fate of modifiers of mutation rate under the three forces and allows us to predict the long-term evolutionary trajectory of mutation rates in asexual organisms. Expand
The evolution of evolvability in genetic programming
TLDR
Several new selection techniques and genetic operators are proposed in order to give better control over the evolution of evolvability and improved evolutionary performance. Expand
Is modularity necessary for evolvability? Remarks on the relationship between pleiotropy and evolvability.
TLDR
The most evolvable genetic architectures may often be those with an intermediate level of integration among characters, and in particular those where pleiotropic effects are variable and able to compensate for each other's constraints. Expand
...
1
2
3
4
5
...