Evolution of EF-hand calcium-modulated proteins. II. Domains of several subfamilies have diverse evolutionary histories

@article{Nakayama2004EvolutionOE,
  title={Evolution of EF-hand calcium-modulated proteins. II. Domains of several subfamilies have diverse evolutionary histories},
  author={Susumu Nakayama and Nancy D Moncrief and Robert H. Kretsinger},
  journal={Journal of Molecular Evolution},
  year={2004},
  volume={34},
  pages={416-448}
}
SummaryIn the first report in this series we described the relationships and evolution of 152 individual proteins of the EF-hand subfamilies. Here we add 66 additional proteins and define eight (CDC, TPNV, CLNB, LPS, DGK, 1 F8, VIS, TCBP) new subfamilies and seven (CAL, SQUD, CDPK, EFH5, TPP, LAV, CRGP) new unique proteins, which we assume represent new subfamilies.The main focus of this study is the classification of individual EF-hand domains. Five subfamilies—calmodulin, troponin C… 
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