Evolution of Dermatofibrosarcoma Protuberans to DFSP-Derived Fibrosarcoma: An Event Marked by Epithelial-Mesenchymal Transition-like Process and 22q Loss.

@article{Stacchiotti2016EvolutionOD,
  title={Evolution of Dermatofibrosarcoma Protuberans to DFSP-Derived Fibrosarcoma: An Event Marked by Epithelial-Mesenchymal Transition-like Process and 22q Loss.},
  author={Silvia Stacchiotti and Annalisa Astolfi and Alessandro Gronchi and Andrea Fontana and Maria Aabbondanza Pantaleo and Tiziana Negri and Monica Brenca and Marcella Tazzari and Milena Urbini and Valentina Indio and Chiara Colombo and Stefano Radaelli and Silvia Brich and Angelo P Dei Tos and Paolo Giovanni Casali and Chiara Castelli and Gian Paolo Dagrada and Silvana Pilotti and Roberta Maestro},
  journal={Molecular cancer research : MCR},
  year={2016},
  volume={14 9},
  pages={820-9}
}
UNLABELLED Dermatofibrosarcoma protuberans (DFSP) is a rare and indolent cutaneous sarcoma. At times, a fibrosarcomatous transformation marked by a more aggressive clinical behavior may be present. We investigated the natural history and the molecular bases of progression from classic DFSP to the fibrosarcomatous form (FS-DFSP), looking, retrospectively, at… CONTINUE READING