Evolution of DNA organization in hypotrichous ciliates.

@article{Prescott1999EvolutionOD,
  title={Evolution of DNA organization in hypotrichous ciliates.},
  author={David M. Prescott},
  journal={Annals of the New York Academy of Sciences},
  year={1999},
  volume={870},
  pages={301-13}
}
Profound changes have been introduced into the germline (micronuclear) and somatic (macronuclear) genomes of hypotrichous ciliates during evolution. First, multiple, short, unique, noncoding sequences, called IESs, have been inserted into micronuclear genes. IESs are spliced out of each gene, and the gene segments, called MDSs, are ligated during conversion of the micronuclear genome to a macronuclear genome after cell mating. The IESs in a particular gene can change dramatically in number… CONTINUE READING