Evolution of DNA base composition under no-strand-bias conditions when the substitution rates are not constant.

@article{Lobry1999EvolutionOD,
  title={Evolution of DNA base composition under no-strand-bias conditions when the substitution rates are not constant.},
  author={J. R. Lobry and Camille Lobry},
  journal={Molecular biology and evolution},
  year={1999},
  volume={16 6},
  pages={719-23}
}
The evolution of DNA base composition evolution is simplified to a six-parameter model when there are no strand biases for mutation and selection. We analyzed the dynamics of this model with special attention to the influence of a change in substitution rates. The G + C content of the DNA sequence tends to an equilibrium value that is controlled by four parameters of the model. When the substitution rates are not constant, the G + C equilibrium position is not constant. The DNA sequence base… CONTINUE READING

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