Evolution of Conus Peptide Genes: Duplication and Positive Selection in the A-Superfamily

@article{Puillandre2010EvolutionOC,
  title={Evolution of Conus Peptide Genes: Duplication and Positive Selection in the A-Superfamily},
  author={Nicolas Puillandre and Maren Watkins and Baldomero M Olivera},
  journal={Journal of Molecular Evolution},
  year={2010},
  volume={70},
  pages={190-202}
}
A remarkable diversity of venom peptides is expressed in the genus Conus (known as “conotoxins” or “conopeptides”). Between 50 and 200 different venom peptides can be found in a single Conus species, each having its own complement of peptides. Conopeptides are encoded by a few gene superfamilies; here we analyze the evolution of the A-superfamily in a fish-hunting species clade, Pionoconus. More than 90 conopeptide sequences from 11 different Conus species were used to build a phylogenetic tree… CONTINUE READING