Evolution of Chordate Actin Genes: Evidence from Genomic Organization and Amino Acid Sequences

@article{Kusakabe1997EvolutionOC,
  title={Evolution of Chordate Actin Genes: Evidence from Genomic Organization and Amino Acid Sequences},
  author={Takehiro G Kusakabe and Isato Araki and Noriyuki Satoh and William R Jeffery},
  journal={Journal of Molecular Evolution},
  year={1997},
  volume={44},
  pages={289-298}
}
The origin and evolutionary relationship of actin isoforms was investigated in chordates by isolating and characterizing two new ascidian cytoplasmic and muscle actin genes. The exon–intron organization and sequences of these genes were compared with those of other invertebrate and vertebrate actin genes. The gene HrCA1 encodes a cytoplasmic (nonmuscle)-type actin, whereas the MocuMA2 gene encodes an adult muscle-type actin. Our analysis of these genes showed that intron positions are conserved… CONTINUE READING

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