Evolution of CST function in telomere maintenance.

@article{Price2010EvolutionOC,
  title={Evolution of CST function in telomere maintenance.},
  author={Carolyn M. Price and Kara A. Boltz and Mary F. Chaiken and Jason A Stewart and Mark A Beilstein and Dorothy E Shippen},
  journal={Cell cycle},
  year={2010},
  volume={9 16},
  pages={3157-65}
}
Telomeres consist of an elaborate, higher-order DNA architecture, and a suite of proteins that provide protection for the chromosome terminus by blocking inappropriate recombination and nucleolytic attack. In addition, telomeres facilitate telomeric DNA replication by physical interactions with telomerase and the lagging strand replication machinery. The prevailing view has been that two distinct telomere capping complexes evolved, shelterin in vertebrates and a trimeric complex comprised of… CONTINUE READING

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