Evolution of CST function in telomere maintenance.

  title={Evolution of CST function in telomere maintenance.},
  author={Carolyn M. Price and Kara A. Boltz and Mary F. Chaiken and Jason A Stewart and Mark A Beilstein and Dorothy E Shippen},
  journal={Cell cycle},
  volume={9 16},
Telomeres consist of an elaborate, higher-order DNA architecture, and a suite of proteins that provide protection for the chromosome terminus by blocking inappropriate recombination and nucleolytic attack. In addition, telomeres facilitate telomeric DNA replication by physical interactions with telomerase and the lagging strand replication machinery. The prevailing view has been that two distinct telomere capping complexes evolved, shelterin in vertebrates and a trimeric complex comprised of… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 69 extracted citations


Publications referenced by this paper.
Showing 1-10 of 58 references

Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology.

Proceedings of the National Academy of Sciences of the United States of America • 2010

A key role for Ctf 4 in coupling the MCM 2 - 7 helicase to DNA polymerase alpha within the eukaryotic repli - some

A Gambus, F vanDeursen, +3 authors RD Edmondson
EMBO J • 2009

Similar Papers

Loading similar papers…