Evolution by recombination and transspecies polymorphism in the MHC class I gene of Xenopus laevis.

  title={Evolution by recombination and transspecies polymorphism in the MHC class I gene of Xenopus laevis.},
  author={D. H. Bos and Bruce Waldman},
  journal={Molecular biology and evolution},
  volume={23 1},
  • D. H. Bos, Bruce Waldman
  • Published 2006
  • Biology, Medicine
  • Molecular biology and evolution
  • The patterns of major histocompatibility complex (MHC) evolution involve duplications, deletions, and independent divergence of loci during episodes punctuated by natural selection. Major differences in MHC evolution among taxa have previously been attributed to variation in linkage patterns of class I and class II MHC genes. Here we characterize patterns of evolution in the MHC class Ia gene of Xenopus laevis in terms of polymorphism, recombination, and extent of transspecies polymorphism. We… CONTINUE READING
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