Evolution and variation of renin genes in mice.

  title={Evolution and variation of renin genes in mice.},
  author={Douglas P Dickinson and Kenneth W. Gross and Nina Piccini and Curtis M. Wilson},
  volume={108 3},
Inbred strains of mice carry Ren-1, a gene encoding the thermostable Renin-1 isozyme. Ren-1 is expressed at relatively low levels in mouse submandibular gland and kidney. Some strains also carry Ren-2, a gene encoding the thermolabile Renin-2 isozyme. Ren-2 is expressed at high levels in the mouse submandibular gland and at very low levels, if at all, in the kidney. Ren-1 and Ren-2 are closely linked on mouse chromosome 1, show extensive homology in coding and noncoding regions and provide a… CONTINUE READING
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