Evolution and pathogenesis of Leptospira spp.: lessons learned from the genomes.

@article{Xue2009EvolutionAP,
  title={Evolution and pathogenesis of Leptospira spp.: lessons learned from the genomes.},
  author={Feng Xue and Jie Yan and Mathieu Picardeau},
  journal={Microbes and infection},
  year={2009},
  volume={11 3},
  pages={
          328-33
        }
}
Leptospirosis has emerged to become a major public health problem in developing countries. The availability of complete sequences of strains representing saprophytic and pathogenic species of the genus Leptospira is providing insights into the evolution of virulence and survival mechanisms used by these bacteria to persist in different ecological niches. 

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