Evolution and organization of a highly dynamic, subtelomeric helicase gene family in the rice blast fungus Magnaporthe grisea.

@article{Gao2002EvolutionAO,
  title={Evolution and organization of a highly dynamic, subtelomeric helicase gene family in the rice blast fungus Magnaporthe grisea.},
  author={Weimin Gao and Chang Hyun Khang and S Park and Yong-Hwan Lee and Seogchan Kang},
  journal={Genetics},
  year={2002},
  volume={162 1},
  pages={103-12}
}
Sequence analysis of a 13-kb telomeric region in O-137, a rice pathogenic isolate of Magnaporthe grisea, uncovered a novel gene, designated TLH1 (telomere-linked helicase 1). The TLH1 gene is a member of a gene family, and the sequences flanking this gene family have also been amplified. Genetic mapping showed that most members of the TLH gene family are tightly linked to the telomeres. A physical mapping technique, termed RecA-mediated Achilles' heel cleavage, and cloning and sequencing of two… CONTINUE READING
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