Evolution Rates of Genes on Leading and Lagging DNA Strands

@article{Szczepanik2001EvolutionRO,
  title={Evolution Rates of Genes on Leading and Lagging DNA Strands},
  author={Dorota Szczepanik and Paweł Mackiewicz and Maria Kowalczuk and Agnieszka Gierlik and Aleksandra Nowicka and Mirosław R. Dudek and Stanisław Cebrat},
  journal={Journal of Molecular Evolution},
  year={2001},
  volume={52},
  pages={426-433}
}
Abstract. One of the main causes of bacterial chromosome asymmetry is replication-associated mutational pressure. Different rates of nucleotide substitution accumulation on leading and lagging strands implicate qualitative and quantitative differences in the accumulation of mutations in protein coding sequences lying on different DNA strands. We show that the divergence rate of orthologs situated on leading strands is lower than the divergence rate of those situated on lagging strands. The… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 21 CITATIONS

The replication-related organization of bacterial genomes.

  • Microbiology
  • 2004
VIEW 3 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 69 REFERENCES

A model of evolution

MO Dayhoff, RM Schwartz, BC Orcutt
  • Nature
  • 1978
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

The neutral theory of molecular evolution.

VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

A comparative genomics approach to DNA asymmetry.

  • Annals of the New York Academy of Sciences
  • 1999
VIEW 2 EXCERPTS