Evolution, expansion and expression of the Kunitz/BPTI gene family associated with long-term blood feeding in Ixodes Scapularis

@article{Dai2011EvolutionEA,
  title={Evolution, expansion and expression of the Kunitz/BPTI gene family associated with long-term blood feeding in Ixodes Scapularis},
  author={Shao-xing Dai and Ai-di Zhang and Jing-Fei Huang},
  journal={BMC Evolutionary Biology},
  year={2011},
  volume={12},
  pages={4 - 4}
}
BackgroundRecent studies of the tick saliva transcriptome have revealed the profound role of salivary proteins in blood feeding. Kunitz/BPTI proteins are abundant in the salivary glands of ticks and perform multiple functions in blood feeding, such as inhibiting blood coagulation, regulating host blood supply and disrupting host angiogenesis. However, Kunitz/BPTI proteins in soft and hard ticks have different functions and molecular mechanisms. How these differences emerged and whether they are… 
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