Evolution, development and timing of puberty

  title={Evolution, development and timing of puberty},
  author={Peter D. Gluckman and Mark A. Hanson},
  journal={Trends in Endocrinology \& Metabolism},
  • P. Gluckman, M. Hanson
  • Published 31 January 2006
  • Medicine, Biology
  • Trends in Endocrinology & Metabolism
Changing times: The evolution of puberty
Precocious Puberty in Internationally Adopted Girls
The challenge is to establish guidelines that ensure appropriate recognition of those adopted children who need medical examinations for precocious puberty and to identify the subgroup of patients who will benefit from treatment with GnRH analogs.
Nutritional Determinants of the Timing of Puberty.
Evidence for prenatal nutrition, infant feeding practices, and childhood intake of fat, carbohydrate, and micronutrients is inconsistent and secondary analyses of prenatal and early-life randomized nutritional interventions with extended follow-up through peripubertal years would help clarify the role of nutrition.
[Does childhood obesity affect sexual development?].
The latest studies and evidence on the relationship between body composition in children and the rate and timing of puberty are presented, underlining the inconsistencies in the data and the need for further research in this area.
Assessment and mechanism of variations in pubertal timing in internationally adopted children: a developmental hypothesis
During the past decades, children migrating for international adoption have increased in number. creating an original condition of dramatic environmental change during development. In several
Effects of obesity on human sexual development
Evidence in girls is less clear, with the majority of studies showing obesity to be associated with earlier puberty and voice break, although a subgroup of boys with obesity exhibits late puberty, perhaps as a variation of constitutional delay in growth and puberty.
Pros and cons of GnRHa treatment for early puberty in girls
GnRHa therapy is effective in improving adult height in patients who present with classic central precocious puberty (at <8 years old), without causing adverse effects on body composition, BMD and reproductive function, but its benefits in patients with atypical forms of early puberty not driven by luteinising hormone are not well defined.
History and Trends of Pubertal Development in Females
The history and trends pertaining to pubertal development over time are outlined in this chapter.
Determinants of pubertal development in an urban South African cohort
The main aims of this study were to investigate the timing of, and the early life factors associated with pubertal development and age at menarche in Black and White urban South African adolescents, and logistic regression models showed that a greater weight and height velocity in late childhood significantly increased the odds of achieving early breasU genitalia development.


The Effects of Manipulation of Puberty on Growth
  • Peter A. Lee
  • Biology, Medicine
    Hormone Research in Paediatrics
  • 2003
The combination of GH and gonadotropin-releasing hormone analogues greatly enhances growth and their separate and combined use for the treatment of GH deficiency, central precocious puberty and other diagnoses in children and adolescents is discussed in this article.
The timing of normal puberty and the age limits of sexual precocity: variations around the world, secular trends, and changes after migration.
These observations urge further study of the onset of puberty as a possible sensitive and early marker of the interactions between environmental conditions and genetic susceptibility that can influence physiological and pathological processes.
Secular Trends in Pubertal Development
More longitudinal studies are needed to understand the short- and long-term consequences of secular changes in both final height and pubertal development before the authors know how important the trends are.
Intrauterine growth retardation and puberty in girls.
It is not clear, however, whether the findings of an earlier onset of puberty in IUGR-girls merely reflect a more rapid progression of puberty, and parallels can be drawn between hypotheses on the longterm consequences of IugR and hypotheses onThe initiation of puberty.
Early Puberty in Adopted Children
The current understanding of early puberty in adopted children is reviewed, including prevalence, background and treatment options, as well as auxological aspects, psychological items are addressed.
Morbidity mortality and menarche.
It is suggested in this discussion that the secular trend in maturation is best viewed as an aspect of the demographic transition in mortality which in turn can be ascribed to improvements in medical
Morbidity, morality, and menarche.
: It is suggested in this discussion that the secular trend in maturation is best viewed as an aspect of the demographic transition in mortality, which in turn can be ascribed to improvements in
The secular trend in size and maturational timing and its implications for nutritional assessment.
  • S. Garn
  • Medicine
    The Journal of nutrition
  • 1987
For most westernized countries there has been a marked intergenerational increase in size and a decrease in the age at menarche, both interrupted or temporarily reversed during economic disruption or
Age at menarche: a misunderstanding.
Drawing on historical documentation from classical Roman medieval Islamic and 19th and 20th century sources it is suggested that the change in the age of menarche from 17 years in the 19th century to
Heritability of age at menarche in girls from the Fels Longitudinal Study.
It is reasonable to consider it well-established that approximately half the phenotypic variation among girls from developed nations in the timing of menarche is due to genetic factors.