Evolution, biogenesis and function of promoter-associated RNAs.

  title={Evolution, biogenesis and function of promoter-associated RNAs.},
  author={Ryan J. Taft and Craig D Kaplan and Cas Simons and John S. Mattick},
  journal={Cell cycle},
  volume={8 15},
Transcription initiation is a tightly controlled process that involves chromatin modifications and nucleosome remodelling, transcription factor binding, and the assembly and recruitment of the RNA Polymerase II (RNAPII) complex. Recent studies have reported a diversity of long and short RNAs derived from eukaryotic promoters, which may be involved in transcription regulation. Here we review these species with particular attention to the features and biogenesis of transcription initiation RNAs… CONTINUE READING

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