Evolocumab lowers LDL-C safely and effectively when self-administered in the at-home setting

  title={Evolocumab lowers LDL-C safely and effectively when self-administered in the at-home setting},
  author={Ricardo E Dent and Raju Joshi and C. Stephen Djedjos and Jason C. Legg and Mary Grace Elliott and Michelle L. Geller and Dawn Meyer and Ransi Somaratne and Chris P Recknor and Robert Jason Weiss},
Evolocumab has been shown to consistently reduce low-density lipoprotein cholesterol (LDL-C) across populations. The phase 3 studies included administration in the home-use and in-clinic settings but did not specifically evaluate the feasibility of home-use administration. Two clinical studies enrolled patients with hypercholesterolemia or mixed dyslipidemia on statin therapy and with/without ezetimibe received evolocumab in the home-use setting. Patients were randomized to self-administer… CONTINUE READING
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  • EA Stein, RP Giugliano, +11 authors MS Sabatine
  • N Engl J Med
  • 2015

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  • https://www.kynamro.com/~/media/Kynamro/Files…
  • 2015

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  • FJ Raal, EA Stein, +13 authors D Gaudet
  • 2015

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  • JG Robinson, BS Nedergaard, +9 authors R Weiss
  • 2015

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