Evoked otoacoustic emissions and pure tone threshold audiometry in patients receiving cisplatinum therapy.

@article{Zorowka1993EvokedOE,
  title={Evoked otoacoustic emissions and pure tone threshold audiometry in patients receiving cisplatinum therapy.},
  author={Patrick Georg Zorowka and H J Schmitt and Peter Gutjahr},
  journal={International journal of pediatric otorhinolaryngology},
  year={1993},
  volume={25 1-3},
  pages={73-80}
}
Eight children and young adults with cancer were evaluated serially using pure tone audiometry as well as registration of click-evoked otoacoustic emissions (EOAE) 1 day prior to therapy as well as after various numbers of doses of cisplatinum. A reduction of EOAE-amplitudes following cisplatinum therapy was observed in all patients. This reduction tended to recover after the end of cisplatinum administration. Since EOAE are believed to result from cochlear bio-mechanical processes, the reduced… CONTINUE READING