Evoked effects of oestradiol on hepatic cholesterol 7 alpha-hydroxylase and drug oxidase in castrated rats.

Abstract

1. Oestradiol administration in castrated rats resulted in an increased activity of the cholesterol 7 alpha-hydroxylase and a decreased activity of the drug oxidase enzyme systems. 2. Aqueous solutions of oestradiol (up to 25.10(-6)M) incubated in vitro with microsomes, binds into the microsomal membrane framework reducing the activity of both enzyme… (More)

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@article{Deliconstantinos1982EvokedEO, title={Evoked effects of oestradiol on hepatic cholesterol 7 alpha-hydroxylase and drug oxidase in castrated rats.}, author={George Deliconstantinos and George Ramantanis}, journal={The International journal of biochemistry}, year={1982}, volume={14 9}, pages={811-5} }