Evodiamine activates cellular apoptosis through suppressing PI3K/AKT and activating MAPK in glioma

@inproceedings{Wang2018EvodiamineAC,
  title={Evodiamine activates cellular apoptosis through suppressing PI3K/AKT and activating MAPK in glioma},
  author={Rong Wang and Danni Deng and Naiyuan Shao and Yuan Xu and Lian Bi Xue and Ya Peng and Yatian Liu and Feng Zhi},
  booktitle={OncoTargets and therapy},
  year={2018}
}
Background Glioblastoma multiforme (GBM) is the most malignant primary tumor of the central nervous system and is associated with a very poor prognosis. No further improvements in outcomes have been reported since radiotherapy-temozolomide therapy was introduced. Therefore, developing new agents to treat GBM is important. Aim This study aimed to evaluate… CONTINUE READING