Evo-Devo and an Expanding Evolutionary Synthesis: A Genetic Theory of Morphological Evolution
@article{Carroll2008EvoDevoAA, title={Evo-Devo and an Expanding Evolutionary Synthesis: A Genetic Theory of Morphological Evolution}, author={S. Carroll}, journal={Cell}, year={2008}, volume={134}, pages={25-36} }
Biologists have long sought to understand which genes and what kinds of changes in their sequences are responsible for the evolution of morphological diversity. Here, I outline eight principles derived from molecular and evolutionary developmental biology and review recent studies of species divergence that have led to a genetic theory of morphological evolution, which states that (1) form evolves largely by altering the expression of functionally conserved proteins, and (2) such changes… CONTINUE READING
Paper Mentions
1,506 Citations
Arguments in the evo-devo debate: say it with flowers!
- Biology, Medicine
- Journal of experimental botany
- 2014
- 19
- PDF
Plant 'evo-devo' goes genomic: from candidate genes to regulatory networks.
- Biology, Medicine
- Trends in plant science
- 2012
- 18
Experimental approaches to evaluate the contributions of candidate cis-regulatory mutations to phenotypic evolution.
- Biology, Medicine
- Methods in molecular biology
- 2011
- 15
- Highly Influenced
- PDF
Contrasting genetic paths to morphological and physiological evolution
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 2010
- 58
- PDF
Comparative studies of gene expression and the evolution of gene regulation
- Biology, Medicine
- Nature Reviews Genetics
- 2012
- 329
- PDF
Evolutionary developmental biology its roots and characteristics.
- Biology, Medicine
- Developmental biology
- 2011
- 9
References
SHOWING 1-10 OF 124 REFERENCES
THE LOCUS OF EVOLUTION: EVO DEVO AND THE GENETICS OF ADAPTATION
- Biology, Medicine
- Evolution; international journal of organic evolution
- 2007
- 882
- PDF
Resynthesizing evolutionary and developmental biology.
- Biology, Medicine
- Developmental biology
- 1996
- 589
- Highly Influential
- PDF
Evo-Devo: evolutionary developmental mechanisms.
- Biology, Medicine
- The International journal of developmental biology
- 2003
- 131
The evolutionary significance of cis-regulatory mutations
- Biology, Medicine
- Nature Reviews Genetics
- 2007
- 1,308
- PDF
Morphological evolution through multiple cis-regulatory mutations at a single gene
- Biology, Medicine
- Nature
- 2007
- 301
- PDF
The Evolution of Gene Regulation Underlies a Morphological Difference between Two Drosophila Sister Species
- Biology, Medicine
- Cell
- 2008
- 249
- PDF
A role of Ultrabithorax in morphological differences between Drosophila species
- Medicine, Biology
- Nature
- 1998
- 237
- PDF
Evolutionary plasticity of developmental gene regulatory network architecture
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 2007
- 146
- Highly Influential
- PDF