Evo-Devo and an Expanding Evolutionary Synthesis: A Genetic Theory of Morphological Evolution

@article{Carroll2008EvoDevoAA,
  title={Evo-Devo and an Expanding Evolutionary Synthesis: A Genetic Theory of Morphological Evolution},
  author={S. Carroll},
  journal={Cell},
  year={2008},
  volume={134},
  pages={25-36}
}
  • S. Carroll
  • Published 2008
  • Biology, Medicine
  • Cell
  • Biologists have long sought to understand which genes and what kinds of changes in their sequences are responsible for the evolution of morphological diversity. Here, I outline eight principles derived from molecular and evolutionary developmental biology and review recent studies of species divergence that have led to a genetic theory of morphological evolution, which states that (1) form evolves largely by altering the expression of functionally conserved proteins, and (2) such changes… CONTINUE READING
    1,506 Citations

    Figures and Topics from this paper

    Explore Further: Topics Discussed in This Paper

    Arguments in the evo-devo debate: say it with flowers!
    • 19
    • PDF
    Experimental approaches to evaluate the contributions of candidate cis-regulatory mutations to phenotypic evolution.
    • 15
    • Highly Influenced
    • PDF
    Contrasting genetic paths to morphological and physiological evolution
    • 58
    • PDF
    Comparative studies of gene expression and the evolution of gene regulation
    • 329
    • PDF
    Evolutionary developmental biology its roots and characteristics.
    • M. Morange
    • Biology, Medicine
    • Developmental biology
    • 2011
    • 9

    References

    SHOWING 1-10 OF 124 REFERENCES
    THE LOCUS OF EVOLUTION: EVO DEVO AND THE GENETICS OF ADAPTATION
    • H. Hoekstra, J. Coyne
    • Biology, Medicine
    • Evolution; international journal of organic evolution
    • 2007
    • 882
    • PDF
    Evo-devo: the evolution of a new discipline
    • R. Raff
    • Biology, Medicine
    • Nature Reviews Genetics
    • 2000
    • 240
    • PDF
    Resynthesizing evolutionary and developmental biology.
    • 589
    • Highly Influential
    • PDF
    Evo-Devo: evolutionary developmental mechanisms.
    • B. Hall
    • Biology, Medicine
    • The International journal of developmental biology
    • 2003
    • 131
    The evolutionary significance of cis-regulatory mutations
    • G. Wray
    • Biology, Medicine
    • Nature Reviews Genetics
    • 2007
    • 1,308
    • PDF
    PERSPECTIVE: EVOLUTIONARY DEVELOPMENTAL BIOLOGY AND THE PROBLEM OF VARIATION
    • 199
    Morphological evolution through multiple cis-regulatory mutations at a single gene
    • 301
    • PDF
    A role of Ultrabithorax in morphological differences between Drosophila species
    • 237
    • PDF
    Evolutionary plasticity of developmental gene regulatory network architecture
    • 146
    • Highly Influential
    • PDF