Evisceration of Mouse Vitreous and Retina for Proteomic Analyses

  title={Evisceration of Mouse Vitreous and Retina for Proteomic Analyses},
  author={Jessica Marie Skeie and Stephen H Tsang and Vinit B Mahajan},
  booktitle={Journal of visualized experiments : JoVE},
While the mouse retina has emerged as an important genetic model for inherited retinal disease, the mouse vitreous remains to be explored. The vitreous is a highly aqueous extracellular matrix overlying the retina where intraocular as well as extraocular proteins accumulate during disease.(1-3) Abnormal interactions between vitreous and retina underlie several diseases such as retinal detachment, proliferative diabetic retinopathy, uveitis, and proliferative vitreoretinopathy.(1,4) The relative… CONTINUE READING
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