Evidences for the existence of a low dopaminergic tone in polycystic ovarian syndrome: implications for OHSS development and treatment.

@article{Gmez2011EvidencesFT,
  title={Evidences for the existence of a low dopaminergic tone in polycystic ovarian syndrome: implications for OHSS development and treatment.},
  author={Ra{\'u}l Aguero G{\'o}mez and Hortensia Ferrero and Francisco Delgado-Rosas and Mar{\'i}a Gayt{\'a}n and Concepci{\'o}n Morales and Ralf Zimmermann and Carlos Sim{\'o}n and Francisco X Gayt{\'a}n and Antonio Pellicer},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2011},
  volume={96 8},
  pages={2484-92}
}
CONTEXT The dopamine/dopamine receptor 2 (D2/Drd2) pathway modulates vascular endothelial growth factor (VEGF)-dependent vascular permeability and angiogenesis in the ovary. Deregulation of the VEGF/VEGF receptor (VEGFR)-2 pathway leading to increased risk of ovarian hyperstimulation syndrome has been described in the ovary of patients suffering from polycystic ovarian syndrome (PCOS). OBJECTIVE The objective of the study was to ascertain whether deregulation of the VEGF/VEGFR-2 might a least… CONTINUE READING
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