Evidences for salbutamol metabolism by respiratory and liver cell lines.

@article{Nakpheng2017EvidencesFS,
  title={Evidences for salbutamol metabolism by respiratory and liver cell lines.},
  author={T. Nakpheng and Supreedee Songkarak and T. Suwandecha and Rutthapol Sritharadol and Charisopon Chunhachaichana and T. Srichana},
  journal={Drug metabolism and pharmacokinetics},
  year={2017},
  volume={32 2},
  pages={
          127-134
        }
}
This study aimed to investigate the enantiomeric biotransformation of salbutamol in the human respiratory and liver cells. The cells from the different cell growth cycles were treated with various concentrations of salbutamol sulfate. Salbutamol and its metabolites were analyzed using chiral liquid chromatography and mass spectrometry. There were no metabolites of salbutamol found in the extracellular medium, intracellular, and cell lysate of respiratory cell lines. The S/R ratios of salbutamol… Expand
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