Evidence that tumor necrosis factor alpha (TNF)-induced activation of neutrophil respiratory burst on biologic surfaces is mediated by the p55 TNF receptor.

@article{Menegazzi1994EvidenceTT,
  title={Evidence that tumor necrosis factor alpha (TNF)-induced activation of neutrophil respiratory burst on biologic surfaces is mediated by the p55 TNF receptor.},
  author={Renzo Menegazzi and Rita Cramer and Pierluigi Patriarca and Peter Scheurich and Pietro Dri},
  journal={Blood},
  year={1994},
  volume={84 1},
  pages={287-93}
}
Polymorphonuclear leukocytes (PMN) residing on biologic surfaces respond with a vigorous respiratory burst when exposed to tumor necrosis factor alpha (TNF). PMN possess both the p55 and the p75 TNF receptors, but their role in the elicitation of the respiratory burst is not known. We addressed this problem by studying the effect of monoclonal antibodies (MoAbs) directed against the p55 TNF receptor (MoAb H398 and MoAb htr-9) and the p75 TNF receptor (MoAb utr-1) on TNF-induced production of O2… CONTINUE READING
20 Citations
48 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 48 references

Agonistic and antagonistic antibodies as a tool to study the functional role of human tumor necrosis factor receptors

  • TA Waldmann
  • Tumor Necrosis Factor : Molecular and Cellular…
  • 1993

Expres - sion and functional role of tumor necrosis factor receptors on leukemic cells from patients with type B chronic lymphoproliferative disorders

  • DF Bainton, LJ Miller, TK Kishimoto, TA Springer
  • Blood
  • 1993

Goeddel DP: Two TNF receptors

  • LA Tartaglia
  • Immunol Today
  • 1992

Similar Papers

Loading similar papers…