Evidence that three structural genes code for human alkaline phosphatases

@article{Seargeant1979EvidenceTT,
  title={Evidence that three structural genes code for human alkaline phosphatases},
  author={Lorne E Seargeant and Robert A. Stinson},
  journal={Nature},
  year={1979},
  volume={281},
  pages={152-154}
}
The number of structural gene loci that code for the different molecular forms of human alkaline phosphatase is unknown. Physical properties of the enzymes, immunological data, chemical inhibition and genetic studies suggest that at least three structural genes1 are involved: one coding for alkaline phosphatase from placenta, another for the enzyme from intestine, and one or more for the enzymes from liver, kidney and bone. Badger and Sussman2 have shown that alkaline phosphatases from human… CONTINUE READING

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