Evidence that the gonadotrophs are the likely site of production of angiotensin II in the anterior pituitary of the rat.

@article{Deschepper1986EvidenceTT,
  title={Evidence that the gonadotrophs are the likely site of production of angiotensin II in the anterior pituitary of the rat.},
  author={Christian F. Deschepper and Debbie Crumrine and William F. Ganong},
  journal={Endocrinology},
  year={1986},
  volume={119 1},
  pages={36-43}
}
To determine whether the angiotensin II-like immunoreactivity (AII-IR) previously reported in rat gonadotrophs is generated locally, we stained for AII-IR in neonatal rat pituitary explants and dispersed adult pituitary cells maintained in serum-free medium. In both preparations, AII-IR was found in cells with the morphological characteristics of gonadotrophs. In the anterior pituitaries of adult male rats, AII-IR and LH beta immunoreactivity were found by electron microscopy to be located in… CONTINUE READING