Evidence that the availability of an allylic hydrogen governs the regioselectivity of the Wacker oxidation.

Abstract

The allylic hydrogen is found to have a dramatic effect on the regioselectivity of the Wacker oxidation, leading to the postulation that an agostic hydrogen or enyl (sigma + pi) complex helps to stabilise the key intermediate.

Cite this paper

@article{Gaunt2001EvidenceTT, title={Evidence that the availability of an allylic hydrogen governs the regioselectivity of the Wacker oxidation.}, author={Matthew J Gaunt and Jinquan Yu and Jonathan Spencer}, journal={Chemical communications}, year={2001}, volume={18}, pages={1844-5} }