Evidence that spinal endorphin mediates intraventricular β-endorphin-induced tail flick inhibition and catalepsy

@article{Tseng1984EvidenceTS,
  title={Evidence that spinal endorphin mediates intraventricular β-endorphin-induced tail flick inhibition and catalepsy},
  author={L. L. -F. Tseng and James M Fujimoto},
  journal={Brain Research},
  year={1984},
  volume={302},
  pages={231-237}
}
Naloxone injected intrathecally had a different effect on the inhibition of the inhibition of the tail flick response produced by beta-endorphin and morphine injected intraventricularly. The intrathecal naloxone completely antagonized the effect of beta-endorphin but had only a very weak effect on morphine. In the same rats the cataleptic response to beta-endorphin was antagonized as well; however no definitive conclusion could be made regarding the antagonism of the morphine-induced catalepsy… CONTINUE READING