Evidence that post-tetanic potentiation is mediated by neuropeptide release in Aplysia.

@article{Fox2001EvidenceTP,
  title={Evidence that post-tetanic potentiation is mediated by neuropeptide release in Aplysia.},
  author={Lyle E Fox and Philip E. Lloyd},
  journal={Journal of neurophysiology},
  year={2001},
  volume={86 6},
  pages={2845-55}
}
Many neuromuscular and central synapses exhibit activity-dependent plasticity. The sustained high-frequency firing needed to elicit some forms of plasticity are similar to those often required to release neuropeptides. We wanted to determine if neuropeptide release could contribute to post-tetanic potentiation (PTP) and chose neuromuscular synapses in buccal muscle I3a to explore this issue. This muscle is innervated by two motor neurons (termed B3 and B38) that show PTP in response to tetanic… CONTINUE READING
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