Evidence that oxidative stress is linked to anxiety-related behaviour in mice

@article{Rammal2008EvidenceTO,
  title={Evidence that oxidative stress is linked to anxiety-related behaviour in mice},
  author={Hassan Rammal and Jaouad Bouayed and Chafique Younos and Rachid Soulimani},
  journal={Brain, Behavior, and Immunity},
  year={2008},
  volume={22},
  pages={1156-1159}
}
Oxidative stress in central and peripheral systems is involved in many diseases, including cancer, cardiovascular diseases, neurodegenerative diseases and several psychiatric disorders. In the present study, the brain and peripheral oxidative status of non-anxious and anxious mice was evaluated using 2',7'-dichlorofluorescin diacetate (DCFH-DA), a sensor of reactive oxygen species (ROS). Here we report that anxiety levels are linked to the oxidative status in both neuronal and glial cells in… CONTINUE READING

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