Evidence that obesity alters the quality of oocytes and embryos.

  title={Evidence that obesity alters the quality of oocytes and embryos.},
  author={Rebecca L Robker},
  journal={Pathophysiology : the official journal of the International Society for Pathophysiology},
  volume={15 2},
Infertility is more common in overweight and obese women, with reproductive impairments occurring at many levels of the hypothalamic-ovarian-uterine axis. These impairments lead primarily to longer times to conception and decreased pregnancy rates and have resulted in increasing numbers of overweight and obese women seeking assisted reproduction technologies, such as in vitro fertilization or IVF. Even after undertaking IVF procedures obese women have decreased pregnancy rates compared to… CONTINUE READING


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Peroxisome proliferator - activated receptor gamma agonist rosiglitazone reverses the adverse effects of dietinduced obesity on oocyte quality

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