Evidence that mobile lipids detected in rat brain glioma by 1H nuclear magnetic resonance correspond to lipid droplets.

@article{Remy1997EvidenceTM,
  title={Evidence that mobile lipids detected in rat brain glioma by 1H nuclear magnetic resonance correspond to lipid droplets.},
  author={Christelle Remy and N Fouilh{\'e} and Ignasi Barba and E Sam-La{\"i} and Hana Lahrech and M Gr{\`a}cia Cucurella and M. Izquierdo and Alberto Moreno and Anne Marie Ziegler and Raphael Massarelli and Michel D{\'e}corps and Carles Ar{\'u}s},
  journal={Cancer research},
  year={1997},
  volume={57 3},
  pages={407-14}
}
Mobile lipids have been detected by proton nuclear magnetic resonance (NMR) in animal and human tumors (cultured cells, biopsies, and in vivo), but their origin and subcellular location are still unclear. They have been associated with malignancy, metastatic ability, drug resistance, and necrosis. We wanted to determine whether these lipids are located within plasma membrane microdomains or in lipid droplets for a C6 cell-induced rat glioma. NMR-visible mobile lipids were found in all… CONTINUE READING
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