Evidence that mechanisms of fin development evolved in the midline of early vertebrates

@article{Freitas2006EvidenceTM,
  title={Evidence that mechanisms of fin development evolved in the midline of early vertebrates},
  author={R. Freitas and Guangjun Zhang and M. Cohn},
  journal={Nature},
  year={2006},
  volume={442},
  pages={1033-1037}
}
  • R. Freitas, Guangjun Zhang, M. Cohn
  • Published 2006
  • Biology, Medicine
  • Nature
  • The origin of paired appendages was a major evolutionary innovation for vertebrates, marking the first step towards fin- (and later limb-) driven locomotion. The earliest vertebrate fossils lack paired fins but have well-developed median fins, suggesting that the mechanisms of fin development were assembled first in the midline. Here we show that shark median fin development involves the same genetic programs that operate in paired appendages. Using molecular markers for different cell types… CONTINUE READING
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